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{"sheet":"Factor Data","index":0,"n_rows":29,"n_cols":8,"rows_kept":29,"cut":false,"hidden":true,"merged":[]}
["Entry Count",3]
["Next Available ID",16]
[]
["ID",11]
["IsActive",true]
["NodeID",40]
["ArcID",55]
["fNodeCopyID"]
["RootNodeID",40]
["FactorName","Mortality"]
["IsHidden",false]
[]
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["IsActive",true]
["NodeID",55,56]
["ArcID",73,74]
["fNodeCopyID"]
["RootNodeID",55]
["FactorName","Dis"]
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[]
["ID",15]
["IsActive",true]
["NodeID",57,58,59,60,61,62]
["ArcID",75,76,77,78,79,80,81]
["fNodeCopyID",13,14]
["RootNodeID",57]
["FactorName","Test"]
["IsHidden",false]

{"sheet":"Node Data","index":1,"n_rows":110,"n_cols":3,"rows_kept":110,"cut":false,"hidden":true,"merged":[]}
["Entry Count",9]
["Next Available ID",63]
[]
["ID",40]
["nParentFactorID",11]
["NodeCopyID"]
["PredecessorArcID"]
["SuccessorArcID",55]
["QualityFactor",1]
["CostFactor",0]
["IsKeyNode",false]
["NodeName","Alive"]
["Rounded",true]
["nTriggerID"]
[]
["ID",55]
["nParentFactorID",14]
["NodeCopyID"]
["PredecessorArcID"]
["SuccessorArcID",73]
["QualityFactor",1]
["CostFactor",0]
["IsKeyNode",false]
["NodeName","Healthy"]
["Rounded",true]
["nTriggerID"]
[]
["ID",56]
["nParentFactorID",14]
["NodeCopyID"]
["PredecessorArcID",73]
["SuccessorArcID",74]
["QualityFactor","ID 9"]
["CostFactor",0]
["IsKeyNode",false]
["NodeName","Disease"]
["Rounded",true]
["nTriggerID"]
[]
["ID",57]
["nParentFactorID",15]
["NodeCopyID",13,14]
["PredecessorArcID"]
["SuccessorArcID",75]
["QualityFactor",1]
["CostFactor",0]
["IsKeyNode",false]
["NodeName","Wait"]
["Rounded",true]
["nTriggerID"]
[]
["ID",58]
["nParentFactorID",15]
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["NodeName","Test"]
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["nTriggerID"]
[]
["ID",59]
["nParentFactorID",15]
["NodeCopyID"]
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["QualityFactor",1]
["CostFactor",0]
["IsKeyNode",false]
["NodeName","Negative"]
["Rounded",true]
["nTriggerID"]
[]
["ID",60]
["nParentFactorID",15]
["NodeCopyID"]
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["SuccessorArcID",81,79]
["QualityFactor",1]
["CostFactor",0]
["IsKeyNode",false]
["NodeName","Positive"]
["Rounded",true]
["nTriggerID"]
[]
["ID",61]
["nParentFactorID",15]
["NodeCopyID"]
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["SuccessorArcID",80]
["QualityFactor",1]
["CostFactor",0]
["IsKeyNode",false]
["NodeName","False"]
["Rounded",true]
["nTriggerID"]
[]
["ID",62]
["nParentFactorID",15]
["NodeCopyID"]
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["SuccessorArcID"]
["QualityFactor",1]
["CostFactor",0]
["IsKeyNode",false]
["NodeName","Detected"]
["Rounded",true]
["nTriggerID"]

{"sheet":"Arc Data","index":2,"n_rows":122,"n_cols":2,"rows_kept":122,"cut":false,"hidden":true,"merged":[]}
["Entry Count",10]
["Next Available ID",82]
[]
["ID",55]
["aParentFactorID",11]
["Stochastic",true]
["Orientation",3.1415927410125732]
["PredecessorNodeID",40]
["SuccessorNodeID",0]
["SuccessorNodeCopyID",0]
["TriggerID"]
["RateProb","rMortUS(Age+_t,Sex)"]
["QualityToll",0]
["CostToll",0]
[]
["ID",73]
["aParentFactorID",14]
["Stochastic",true]
["Orientation",3.1415927410125732]
["PredecessorNodeID",55]
["SuccessorNodeID",56]
["SuccessorNodeCopyID",0]
["TriggerID"]
["RateProb","rDis"]
["QualityToll",0]
["CostToll",0]
[]
["ID",74]
["aParentFactorID",14]
["Stochastic",true]
["Orientation",3.1415927410125732]
["PredecessorNodeID",56]
["SuccessorNodeID",0]
["SuccessorNodeCopyID",0]
["TriggerID"]
["RateProb","mDis"]
["QualityToll",0]
["CostToll",0]
[]
["ID",75]
["aParentFactorID",15]
["Stochastic",true]
["Orientation",3.1415927410125732]
["PredecessorNodeID",57]
["SuccessorNodeID",58]
["SuccessorNodeCopyID",0]
["TriggerID"]
["RateProb","Spike_(tInc)"]
["QualityToll",0]
["CostToll",0]
[]
["ID",76]
["aParentFactorID",15]
["Stochastic",false]
["Orientation",3.1415927410125732]
["PredecessorNodeID",58]
["SuccessorNodeID",59]
["SuccessorNodeCopyID",0]
["TriggerID"]
["RateProb","ID 4"]
["QualityToll",0]
["CostToll",0]
[]
["ID",77]
["aParentFactorID",15]
["Stochastic",false]
["Orientation",3.1415927410125732]
["PredecessorNodeID",59]
["SuccessorNodeID",57]
["SuccessorNodeCopyID",13]
["TriggerID"]
["RateProb",1]
["QualityToll",0]
["CostToll",0]
[]
["ID",78]
["aParentFactorID",15]
["Stochastic",false]
["Orientation",3.1415927410125732]
["PredecessorNodeID",58]
["SuccessorNodeID",60]
["SuccessorNodeCopyID",0]
["TriggerID"]
["RateProb","ID 3"]
["QualityToll",0]
["CostToll",0]
[]
["ID",79]
["aParentFactorID",15]
["Stochastic",false]
["Orientation",3.1415927410125732]
["PredecessorNodeID",60]
["SuccessorNodeID",61]
["SuccessorNodeCopyID",0]
["TriggerID"]
["RateProb","ID 6"]
["QualityToll","tFP"]
["CostToll",0]
[]
["ID",80]
["aParentFactorID",15]
["Stochastic",false]
["Orientation",3.1415927410125732]
["PredecessorNodeID",61]
["SuccessorNodeID",57]
["SuccessorNodeCopyID",14]
["TriggerID"]
["RateProb",1]
["QualityToll",0]
["CostToll",0]
[]
["ID",81]
["aParentFactorID",15]
["Stochastic",false]
["Orientation",3.1415927410125732]
["PredecessorNodeID",60]
["SuccessorNodeID",62]
["SuccessorNodeCopyID",0]
["TriggerID"]
["RateProb","ID 5"]
["QualityToll",0]
["CostToll",0]

{"sheet":"NodeCopy Data","index":3,"n_rows":12,"n_cols":2,"rows_kept":12,"cut":false,"hidden":true,"merged":[]}
["Entry Count",2]
["Next Available ID",15]
[]
["ID",13]
["ncParentFactorID",15]
["NodeOriginalID",57]
["cPredecessorArcID",77]
[]
["ID",14]
["ncParentFactorID",15]
["NodeOriginalID",57]
["cPredecessorArcID",80]

{"sheet":"_Cohort","index":4,"n_rows":47,"n_cols":9,"rows_kept":47,"cut":false,"hidden":false,"merged":[]}
[]
["Cycle Time =",0.1]
["Start Time =",0]
["Time Horizon =",20]
["Discount Rate =",{"$f":"_DiscountRate","v":0.03}]
[null,null,null,"Dis:","Healthy","Disease","Disease","Terminal Node"]
[null,null,null,"Test:","Wait","Wait","Detected"]
[null,null,null,"Mortality:","Alive","Alive","Alive"]
[null,null,null,"Chance/Decision?",0,0,0]
[]
[null,null,null,"Initial Cohort =",1]
[]
[null,null,null,"Time","Counts"]
[null,null,null,{"$f":"IF(_R,_tI,IF(_t>_tF,_tNw,D21))","v":1.6000000000000003},{"$f":"IF(_R,E11,IF(_tNw>=_tF,E14,E21))","v":0.8464100280736937},{"$f":"IF(_R,F11,IF(_tNw>=_tF,F14,F21))","v":5.1510236311285158E-2},{"$f":"IF(_R,G11,IF(_tNw>=_tF,G14,G21))","v":7.4951889583054002E-2},{"$f":"IF(_R,H11,IF(_tNw>=_tF,H14,H21))","v":2.7127846031967242E-2},{"$f":"(SUMPRODUCT(E9:I9,E14:I14) > 0)","v":false}]
[null,null,"Transition Counts:"," Healthy / Wait / Alive ",{"$f":"[1]!xPr([1]!Spike_(tInc)*_dT)*((1-spec)+spec)","v":0}]
[null,null,null," Disease / Wait / Alive ",{"$f":"[1]!xPr(rDis*_dT)","v":9.9501662508318933E-3},{"$f":"[1]!xPr([1]!Spike_(tInc)*_dT)*(1-sens)","v":0}]
[null,null,null," Disease / Detected / Alive "," ",{"$f":"[1]!xPr([1]!Spike_(tInc)*_dT)*sens","v":0}]
[null,null,null,"Terminal Node",{"$f":"[1]!xPr([1]!rMortUS(Age+_t,Sex)*_dT)","v":4.4096881881861005E-4},{"$f":"[1]!xPr((mDis+[1]!rMortUS(Age+_t,Sex))*_dT)","v":2.0233563744420424E-2},{"$f":"[1]!xPr((mDis+[1]!rMortUS(Age+_t,Sex))*_dT)","v":2.0233563744420424E-2}]
[null,null,null,"Entering Counts",{"$f":"SUMPRODUCT(_tR,E15:H15)","v":0},{"$f":"SUMPRODUCT(_tR,E16:H16)","v":8.4219204957045428E-3},{"$f":"SUMPRODUCT(_tR,E17:H17)","v":0},{"$f":"SUMPRODUCT(_tR,E18:H18)","v":2.9320199158539154E-3}]
[null,null,null,"Departing Counts",{"$f":" IF(_CD=1,E14,E14*SUM(E15:E18))","v":8.7951609260204251E-3},{"$f":" IF(_CD=1,F14,F14*SUM(F15:F18))","v":1.0422356498945478E-3},{"$f":" IF(_CD=1,G14,G14*SUM(G15:G18))","v":1.5165438356434843E-3},{"$f":" IF(_CD=1,H14,H14*SUM(H15:H18))","v":0}]
[null,null,null,{"$f":"IF(_CP,D14,D14+_dT)","v":1.7000000000000004},{"$f":"E14+E19-E20","v":0.8376148671476733},{"$f":"F14+F19-F20","v":5.8889921157095147E-2},{"$f":"G14+G19-G20","v":7.3435345747410521E-2},{"$f":"H14+H19-H20","v":3.0059865947821156E-2}]
[]
[null,null,null,"Quality Coefficients (at t):",{"$f":"1","v":1},{"$f":"qDisUndetected","v":0.7},{"$f":"qDisDetected","v":0.9}]
[null,null,null,"(at t+dt):",{"$f":"EXP(-_dR*_dT)","v":0.997004495503373},{"$f":"qDisUndetected*EXP(-_dR*_dT)","v":0.6979031468523611},{"$f":"qDisDetected*EXP(-_dR*_dT)","v":0.8973040459530357}]
[]
[null,null,"Transition QALY Tolls:"," Disease / Wait / Alive ",{"$f":"0","v":0}]
[null,null,null," Healthy / Test / Alive ",{"$f":"[1]!xPr([1]!Spike_(tInc)*_dT)*(1-spec)*tFP","v":0}]
[null,null,null," Disease / Test / Alive "," ",{"$f":"0","v":0}]
[null,null,null,"Terminal Node",{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0}]
[null,null,null,"Incremental QALY Tolls:",{"$f":"IF(_t>_tF,0,_tR*SUM(E26:E29))","v":0},{"$f":"IF(_t>_tF,0,_tR*SUM(F26:F29))","v":0},{"$f":"IF(_t>_tF,0,_tR*SUM(G26:G29))","v":0}]
[null,null,null,"Incremental QALYs:",{"$f":"IF(_t>_tF,0,IF(_CP,0,_dT/2*(E23*E14+E24*E21)))","v":8.4075790806019235E-2},{"$f":"IF(_t>_tF,0,IF(_CP,0,_dT/2*(F23*F14+F24*F21)))","v":3.8578313355661881E-3},{"$f":"IF(_t>_tF,0,IF(_CP,0,_dT/2*(G23*G14+G24*G21)))","v":6.6675266739930064E-3}]
[null,null,null,"Incremental Total:",{"$f":"E31-E30","v":8.4075790806019235E-2},{"$f":"F31-F30","v":3.8578313355661881E-3},{"$f":"G31-G30","v":6.6675266739930064E-3}]
[null,null,null,"Cum Discounted QALYs:",{"$f":"IF(_R,E32,IF(_t>=_tF,E33,E33+E32*EXP(-_dR*_t)))","v":1.4949077639444239},{"$f":"IF(_R,F32,IF(_t>=_tF,F33,F33+F32*EXP(-_dR*_t)))","v":4.0196854944553266E-2},{"$f":"IF(_R,G32,IF(_t>=_tF,G33,G33+G32*EXP(-_dR*_t)))","v":5.5137049105677294E-2}]
[null,null,null,"Overall Cum QALYs =",{"$f":"SUM(E33:G33)","v":1.5902416679946545}]
[]
[null,null,null,"Cost Coefficients (at t):",{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0}]
[null,null,null,"(at t+dt):",{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0}]
[]
[null,null,"Transition Cost Tolls:"," Disease / Wait / Alive "]
[null,null,null," Healthy / Test / Alive "]
[null,null,null," Disease / Test / Alive "]
[null,null,null,"Terminal Node"]
[null,null,null,"Incremental Cost Tolls:"]
[null,null,null,"Incremental Costs:"]
[null,null,null,"Incremental Total:"]
[null,null,null,"Cum Discounted Costs:"]
[null,null,null,"Overall Cum Costs ="]

{"sheet":"Sheet5","index":5,"n_rows":13,"n_cols":11,"rows_kept":13,"cut":false,"hidden":false,"merged":[]}
["Dive Idx","Instig Factor","RateProb","Q Toll","C Toll","From ProDID / To ProdID"]
[1,"Dis","rDis",0,null,"Healthy","Alive","Wait","Disease","Alive","Wait"]
[null,"Mortality","GmpHR(Age+_t,Sex)",0,null,null,null,null,"Terminal Node"]
[]
[2,"Dis","mDis",0,null,"Disease","Alive","Wait","Terminal Node"]
[null,"Mortality","GmpHR(Age+_t,Sex)",0,null,null,null,null,"Terminal Node"]
[null,"Test","Spike_(tInc)*sens",0,null,null,null,null,"Disease","Alive","Detected"]
[]
[3,"Dis","rDis",0,null,"Healthy","Alive","Detected","Disease","Alive","Detected"]
[null,"Mortality","GmpHR(Age+_t,Sex)",0,null,null,null,null,"Terminal Node"]
[]
[4,"Dis","mDis",0,null,"Disease","Alive","Detected","Terminal Node"]
[null,"Mortality","GmpHR(Age+_t,Sex)",0,null,null,null,null,"Terminal Node"]

{"sheet":"Dependency Data","index":6,"n_rows":32,"n_cols":4,"rows_kept":32,"cut":false,"hidden":true,"merged":[]}
["Entry Count",6]
["Next Available ID",10]
[]
["ID",2]
["IfFactorID","**Deleted**"]
["StateID"]
["ThenD","rPE_W","rPE_No","rPE_No"]
[]
["ID",3]
["IfFactorID",14]
["StateID",56,55]
["ThenD","sens","1-spec"]
[]
["ID",4]
["IfFactorID",14]
["StateID",56,55]
["ThenD","1-sens","spec"]
[]
["ID",5]
["IfFactorID",14]
["StateID",56,55]
["ThenD",1,0]
[]
["ID",6]
["IfFactorID",14]
["StateID",56,55]
["ThenD",0,1]
[]
["ID",9]
["IfFactorID",15]
["StateID",62,57]
["ThenD","qDisDetected","qDisUndetected"]

{"sheet":"Trigger Data","index":7,"n_rows":2,"n_cols":2,"rows_kept":2,"cut":false,"hidden":true,"merged":[]}
["Entry Count",0]
["Next Available ID",3]

{"sheet":"_Lookup","index":8,"n_rows":10,"n_cols":2,"rows_kept":10,"cut":false,"hidden":true,"merged":[]}
["Next Available Dive Index",6]
["Begin Table",5]
["End Table",11]
[]
["Lexicographic Node Index","Dive Index"]
[1,1]
[2,2]
[7,3]
[8,4]
[12,5]

{"sheet":"Dis","index":9,"n_rows":16,"n_cols":7,"rows_kept":16,"cut":false,"hidden":false,"merged":[]}
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[null,null,null,null,"rDis =",0.1,"disease incidence (/yr)"]
[null,null,null,null,"mDis = ",0.2,"disease mortality (/yr)"]
[]
[null,null,null,null,"qDisDetected =",0.9,"Quality of life under detected (and therefore treated) disease"]
[null,null,null,null,"qDisUndetected =",0.7,"Quality of life under undetected disease"]

{"sheet":"Test","index":10,"n_rows":21,"n_cols":7,"rows_kept":21,"cut":false,"hidden":false,"merged":[]}
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[null,null,null,null,"tInc =",2,"the test interval (yr)"]
[null,null,null,null,"sens =",0.9,"sensitivity"]
[null,null,null,null,"spec =",0.9,"specificity"]
[null,null,null,null,"tFP =",{"$f":"1/12","v":8.3333333333333329E-2},"toll for false positive test (yr)"]

{"sheet":"Mortality","index":11,"n_rows":4,"n_cols":6,"rows_kept":4,"cut":false,"hidden":false,"merged":[]}
[]
[]
[null,null,null,null,"Age =",50]
[null,null,null,null,"Sex =","Male"]

{"sheet":"Sheet2","index":12,"n_rows":0,"n_cols":0,"rows_kept":0,"cut":false,"hidden":false,"merged":[]}