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{"sheet":"Dependency Data","index":4,"n_rows":12,"n_cols":5,"rows_kept":12,"cut":false,"hidden":true,"merged":[]}
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{"sheet":"_Lookup","index":6,"n_rows":24,"n_cols":2,"rows_kept":24,"cut":false,"hidden":true,"merged":[]}
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[]
["Lexicographic Node Index","Dive Index"]
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[26,12]
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[]
["Cycle Time =",0.1]
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[null,null,null,"Endarterectomy:","(no name)","Post-Surgery Stroke","Post-Surgery Stroke","Post-Surgery Well","Post-Surgery Well","Post-Surgery Well","Stroke","Stroke","Well","Well","Well","Terminal Node"]
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[null,null,null,"Background:","Alive","Alive","Alive","Alive","Alive","Alive","Alive","Alive","Alive","Alive","Alive"]
[null,null,null,"Chance/Decision?",1,0,0,0,0,0,0,0,0,0,0]
[]
[null,null,null,"Initial Cohort =",1]
[]
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[null,null,null," Stroke / Post Small Stroke / Alive ",{"$f":"(1-dSurg)*Pearlystrk*(1-Pbig)","v":0},null,null,null,null,null,null,{"$f":"[1]!xPr(mstroke*_dT)*(1-Pbig)","v":1.6625069357725604E-3}]
[null,null,null," Well / Well / Alive ",{"$f":"(1-dSurg)*(1-Pearlystrk)","v":0}]
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[null,null,null,{"$f":"IF(_CP,D14,D14+_dT)","v":0.6},{"$f":"E14+E27-E28","v":0},2.9870175950836741E-2,2.3819468725532741E-2,0.80538537409065902,1.0213891024746659E-2,8.1982723876839244E-3,0,0,0,0,0,0.12251281782054101]
[]
[null,null,null,"Quality Coefficients (at t):",null,{"$f":"1","v":1},{"$f":"1","v":1},{"$f":"1","v":1},{"$f":"1","v":1},{"$f":"1","v":1},{"$f":"1","v":1},{"$f":"1","v":1},{"$f":"1","v":1},{"$f":"1","v":1},{"$f":"1","v":1}]
[null,null,null,"(at t+dt):",null,{"$f":"EXP(-_dR*_dT)","v":1},1,1,1,1,1,1,1,1,1]
[]
[null,null,"Transition QALY Tolls:"," Post-Surgery Stroke / Post Big Stroke / Alive ",{"$f":"dSurg*(1-Popdie)*Popstroke*Pbig*(1-Pearlydie)*(tSurg+tBig)","v":5.1804444444444441E-3}]
[null,null,null," Post-Surgery Stroke / Post Small Stroke / Alive ",{"$f":"dSurg*(1-Popdie)*Popstroke*(1-Pbig)*tSurg","v":2.0888888888888893E-3}]
[null,null,null," Post-Surgery Well / Well / Alive ",{"$f":"dSurg*(1-Popdie)*(1-Popstroke)*tSurg","v":7.2066666666666668E-2}]
[null,null,null," Stroke / Post Big Stroke / Alive ",{"$f":"(1-dSurg)*Pearlystrk*Pbig*(1-Pearlydie)*tBig","v":0}]
[null,null,null," Stroke / Post Small Stroke / Alive ",{"$f":"0","v":0}]
[null,null,null," Well / Well / Alive ",{"$f":"0","v":0}]
[null,null,null," Post-Surgery Stroke / Big Stroke / Alive "," ",{"$f":"[1]!xPr(EFF*mstroke*Pbig*_dT)*tBig","v":1.3877321242177404E-4}]
[null,null,null," Post-Surgery Stroke / Stroke / Alive "," ",null,{"$f":"[1]!xPr(EFF*mstroke*_dT)*(Pbig*(1-Pearlydie)*tBig+Pbig*Pearlydie*tBig)","v":1.3871542236332861E-4}]
[null,null,null," Post-Surgery Well / Stroke / Alive "," ",null,null,{"$f":"[1]!xPr(mstroke*_dT)*(Pbig*(1-Pearlydie)*tBig+Pbig*Pearlydie*tBig)","v":2.7708448929542664E-4},null,{"$f":"[1]!xPr(EFF*mstroke*_dT)*(Pbig*(1-Pearlydie)*tBig+Pbig*Pearlydie*tBig)","v":1.3871542236332861E-4}]
[null,null,null," Post-Surgery Well / Big Stroke / Alive "," ",null,null,null,{"$f":"[1]!xPr(EFF*mstroke*Pbig*_dT)*tBig","v":1.3877321242177404E-4}]
[null,null,null," Stroke / Big Stroke / Alive "," ",null,null,null,null,null,{"$f":"[1]!xPr(mstroke*Pbig*_dT)*tBig","v":2.7731532878972709E-4}]
[null,null,null," Stroke / Stroke / Alive "," ",null,null,null,null,null,null,{"$f":"[1]!xPr(mstroke*_dT)*(Pbig*(1-Pearlydie)*tBig+Pbig*Pearlydie*tBig)","v":2.7708448929542664E-4}]
[null,null,null," Well / Stroke / Alive "," ",null,null,null,null,null,null,null,{"$f":"[1]!xPr(mstroke*_dT)*(Pbig*(1-Pearlydie)*tBig+Pbig*Pearlydie*tBig)","v":2.7708448929542664E-4},null,{"$f":"[1]!xPr(mstroke*_dT)*(Pbig*(1-Pearlydie)*tBig+Pbig*Pearlydie*tBig)","v":2.7708448929542664E-4}]
[null,null,null," Well / Big Stroke / Alive "," ",null,null,null,null,null,null,null,null,{"$f":"[1]!xPr(mstroke*Pbig*_dT)*tBig","v":2.7731532878972709E-4}]
[null,null,null,"Terminal Node",{"$f":"dSurg*Popdie*tSurg+dSurg*(1-Popdie)*Popstroke*Pbig*Pearlydie*(tSurg+tBig)+(1-dSurg)*Pearlystrk*Pbig*Pearlydie*tBig","v":8.1751111111111104E-3},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0}]
[null,null,null,"Incremental QALY Tolls:",{"$f":"IF(_t>_tF,0,_tR*SUM(E34:E48))","v":0},4.1727772213482529E-6,3.3323522680251396E-6,2.2582288130316476E-4,1.1921372645991914E-6,9.5738504933345973E-7,0,0,0,0,0]
[null,null,null,"Incremental QALYs:",{"$f":"IF(_t>_tF,0,IF(_CP,0,_dT/2*(E31*E14+E32*E29)))","v":0},2.9969607781250612E-3,2.3921204361022652E-3,8.1019092319234307E-2,9.4022170701719759E-4,7.5500323992611453E-4,0,0,0,0,0]
[null,null,null,"Incremental Total:",{"$f":"E50-E49","v":0},2.992788000903713E-3,2.3887880838342401E-3,8.0793269437931137E-2,9.3902956975259837E-4,7.5404585487678108E-4,0,0,0,0,0]
[null,null,null,"Cum Discounted QALYs:",{"$f":"IF(_R,E51,IF(_t>=_tF,E52,E52+E51*EXP(-_dR*_t)))","v":-8.7511111111111109E-2},1.8258134143796633E-2,1.4642320587159616E-2,0.49945404552886535,3.1163499465310909E-3,2.5060075576264604E-3,0,0,0,0,0]
[null,null,null,"Overall Cum QALYs =",{"$f":"SUM(E52:O52)","v":0.45046574665286804}]
[]
[null,null,null,"Cost Coefficients (at t):",null,{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0}]
[null,null,null,"(at t+dt):",null,{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0}]
[]
[null,null,"Transition Cost Tolls:"," Post-Surgery Stroke / Post Big Stroke / Alive ",{"$f":"dSurg*(1-Popdie)*Popstroke*Pbig*(1-Pearlydie)*(cSurg+cBigStrk)","v":1.0878933333333334}]
[null,null,null," Post-Surgery Stroke / Post Small Stroke / Alive ",{"$f":"dSurg*(1-Popdie)*Popstroke*(1-Pbig)*(cSurg+cSmallStrk)","v":0.50133333333333341}]
[null,null,null," Post-Surgery Well / Well / Alive ",{"$f":"dSurg*(1-Popdie)*(1-Popstroke)*cSurg","v":12.972}]
[null,null,null," Stroke / Post Big Stroke / Alive ",{"$f":"(1-dSurg)*Pearlystrk*Pbig*(1-Pearlydie)*cBigStrk","v":0}]
[null,null,null," Stroke / Post Small Stroke / Alive ",{"$f":"(1-dSurg)*Pearlystrk*(1-Pbig)*cSmallStrk","v":0}]
[null,null,null," Well / Well / Alive ",{"$f":"0","v":0}]
[null,null,null," Post-Surgery Stroke / Big Stroke / Alive "," ",{"$f":"0","v":0}]
[null,null,null," Post-Surgery Stroke / Stroke / Alive "," ",null,{"$f":"[1]!xPr(EFF*mstroke*_dT)*(Pbig*(1-Pearlydie)*cBigStrk+Pbig*Pearlydie*cBigStrk+(1-Pbig)*cSmallStrk)","v":3.745316403809873E-2}]
[null,null,null," Post-Surgery Well / Stroke / Alive "," ",null,null,{"$f":"[1]!xPr(mstroke*_dT)*(Pbig*(1-Pearlydie)*cBigStrk+Pbig*Pearlydie*cBigStrk+(1-Pbig)*cSmallStrk)","v":7.4812812109765203E-2},null,{"$f":"[1]!xPr(EFF*mstroke*_dT)*(Pbig*(1-Pearlydie)*cBigStrk+Pbig*Pearlydie*cBigStrk+(1-Pbig)*cSmallStrk)","v":3.745316403809873E-2}]
[null,null,null," Post-Surgery Well / Big Stroke / Alive "," ",null,null,null,{"$f":"0","v":0}]
[null,null,null," Stroke / Big Stroke / Alive "," ",null,null,null,null,null,{"$f":"0","v":0}]
[null,null,null," Stroke / Stroke / Alive "," ",null,null,null,null,null,null,{"$f":"[1]!xPr(mstroke*_dT)*(Pbig*(1-Pearlydie)*cBigStrk+Pbig*Pearlydie*cBigStrk+(1-Pbig)*cSmallStrk)","v":7.4812812109765203E-2}]
[null,null,null," Well / Stroke / Alive "," ",null,null,null,null,null,null,null,{"$f":"[1]!xPr(mstroke*_dT)*(Pbig*(1-Pearlydie)*cBigStrk+Pbig*Pearlydie*cBigStrk+(1-Pbig)*cSmallStrk)","v":7.4812812109765203E-2},null,{"$f":"[1]!xPr(mstroke*_dT)*(Pbig*(1-Pearlydie)*cBigStrk+Pbig*Pearlydie*cBigStrk+(1-Pbig)*cSmallStrk)","v":7.4812812109765203E-2}]
[null,null,null," Well / Big Stroke / Alive "," ",null,null,null,null,null,null,null,null,{"$f":"0","v":0}]
[null,null,null,"Terminal Node",{"$f":"dSurg*Popdie*cSurg+dSurg*(1-Popdie)*Popstroke*Pbig*Pearlydie*(cSurg+cBigStrk)+(1-dSurg)*Pearlystrk*Pbig*Pearlydie*cBigStrk","v":1.5667733333333334},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0},{"$f":"0","v":0}]
[null,null,null,"Incremental Cost Tolls:",{"$f":"IF(_t>_tF,0,_tR*SUM(E58:E72))","v":0},0,8.9973511236678789E-4,6.0972177951854493E-2,0,2.5849396332003414E-4,0,0,0,0,0]
[null,null,null,"Incremental Costs:",{"$f":"IF(_t>_tF,0,IF(_CP,0,_dT/2*(E55*E14+E56*E29)))","v":0},0,0,0,0,0,0,0,0,0,0]
[null,null,null,"Incremental Total:",{"$f":"E74+E73","v":0},0,8.9973511236678789E-4,6.0972177951854493E-2,0,2.5849396332003414E-4,0,0,0,0,0]
[null,null,null,"Cum Discounted Costs:",{"$f":"IF(_R,E75,IF(_t>=_tF,E76,E76+E75*EXP(-_dR*_t)))","v":16.128},0,5.5150182839378047E-3,0.37692249805727651,0,7.8614400405813221E-4,0,0,0,0,0]
[null,null,null,"Overall Cum Costs =",{"$f":"SUM(E76:O76)","v":16.511223660345269}]

{"sheet":"Endarterectomy","index":8,"n_rows":15,"n_cols":20,"rows_kept":15,"cut":false,"hidden":false,"merged":[]}
[]
[]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Popdie =",0.06,"Probability of operative death"]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Popstroke =",0.08,"Probability of operative stroke"]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Pearlystrk =",0.04,"Short-term prob of stroke without surgery"]
[]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"dSurg =",1,"Decision to undergo surgery (1 or 0)"]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"tSurg =",{"$f":"1/12","v":8.3333333333333329E-2},"Toll for surgery (yr)"]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"cSurg =",15,"Cost of surgery (thousands)"]
[]
[]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"dSurg","QALY","Cost"]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,{"$f":"dSurg","v":1},{"$f":"_CumQ","v":0.45046574665286804},{"$f":"_CumC","v":16.511223660345269}]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,1,8.9313101748026789,21.431622193358269]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,0,9.5826112109515478,6.7541585605796532]

{"sheet":"LT_Outome","index":9,"n_rows":7,"n_cols":15,"rows_kept":7,"cut":false,"hidden":false,"merged":[]}
[]
[null,null,null,"EFF =",0.5,"Efficacy of surgery",null,null,null,null,null,null,"cBigStrk =",20,"Cost of a big stroke (thousands)"]
[null,null,null,"mstroke =",0.05,"Rate of stroke (/yr)",null,null,null,null,null,null,"cSmallStrk =",5,"Cost of a small stroke (thousands)"]
[null,null,null,"Pearlydie =",0.38,"Short-term death prob after big stroke",null,null,null,null,null,null,"qPBS =",0.2,"Quality of life post big stroke (/yr)"]
[null,null,null,"Pbig =",{"$f":"2/3","v":0.66666666666666663},"Prob of a big stroke",null,null,null,null,null,null,"qPSS =",0.8,"Quality of life post small stroke (/yr)"]
[null,null,null,"mexcess =",6.5000000000000002E-2,"Excess mortality (/yr)",null,null,null,null,null,null,"tBig =",{"$f":"1/12","v":8.3333333333333329E-2},"Toll for big stroke (yr)"]
[null,null,null,"m0 =",1.106E-2,"Baseline mortality (/yr) (not used - see Background)"]

{"sheet":"Background","index":10,"n_rows":3,"n_cols":5,"rows_kept":3,"cut":false,"hidden":false,"merged":[]}
[]
[null,null,null,"Age =",45]
[null,null,null,"Gender =","Male"]

{"sheet":"Sheet1","index":11,"n_rows":0,"n_cols":0,"rows_kept":0,"cut":false,"hidden":false,"merged":[]}